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Glial cell line-derived neurotrophic factor gene delivery via a polyethylene imine grafted chitosan carrier

Parkinson’s disease is known to result from the loss of dopaminergic neurons. Direct intracerebral injections of high doses of recombinant glial cell line-derived neurotrophic factor (GDNF) have been shown to protect adult nigral dopaminergic neurons. Because GDNF does not cross the blood–brain barr...

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Detalles Bibliográficos
Autores principales:	Peng, Yu-Shiang, Lai, Po-Liang, Peng, Sydney, Wu, His-Chin, Yu, Siang, Tseng, Tsan-Yun, Wang, Li-Fang, Chu, I-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085318/ https://www.ncbi.nlm.nih.gov/pubmed/25061293 http://dx.doi.org/10.2147/IJN.S60465

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