Cargando…
DOTS-Finder: a comprehensive tool for assessing driver genes in cancer genomes
A key challenge in the analysis of cancer genomes is the identification of driver genes from the vast number of mutations present in a cohort of patients. DOTS-Finder is a new tool that allows the detection of driver genes through the sequential application of functional and frequentist approaches,...
Autores principales: | Melloni, Giorgio EM, Ogier, Alessandro GE, de Pretis, Stefano, Mazzarella, Luca, Pelizzola, Mattia, Pelicci, Pier Giuseppe, Riva, Laura |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085541/ https://www.ncbi.nlm.nih.gov/pubmed/25690659 http://dx.doi.org/10.1186/gm563 |
Ejemplares similares
-
LowMACA: exploiting protein family analysis for the identification of rare driver mutations in cancer
por: Melloni, Giorgio E. M., et al.
Publicado: (2016) -
A knowledge-based framework for the discovery of cancer-predisposing variants using large-scale sequencing breast cancer data
por: Melloni, Giorgio E. M., et al.
Publicado: (2017) -
Computational and experimental methods to decipher the epigenetic code
por: de Pretis, Stefano, et al.
Publicado: (2014) -
INSPEcT-GUI Reveals the Impact of the Kinetic Rates of RNA Synthesis, Processing, and Degradation, on Premature and Mature RNA Species
por: de Pretis, Stefano, et al.
Publicado: (2020) -
Dynamics of transcriptional and post-transcriptional regulation
por: Furlan, Mattia, et al.
Publicado: (2020)