Human Growth Hormone Delivery with a Microneedle Transdermal System: Preclinical Formulation, Stability, Delivery and PK of Therapeutically Relevant Doses

This study evaluated the feasibility of coating formulated recombinant human growth hormone (rhGH) on a titanium microneedle transdermal delivery system, Zosano Pharma (ZP)-hGH, and assessed preclinical patch delivery performance. Formulation rheology and surface activity were assessed by viscometry...

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Detalles Bibliográficos
Autores principales: Ameri, Mahmoud, Kadkhodayan, Miryam, Nguyen, Joe, Bravo, Joseph A., Su, Rebeca, Chan, Kenneth, Samiee, Ahmad, Daddona, Peter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085596/
https://www.ncbi.nlm.nih.gov/pubmed/24838219
http://dx.doi.org/10.3390/pharmaceutics6020220

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