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Causes and Consequences of Age-Related Changes in DNA Methylation: A Role for ROS?
Recent genome-wide analysis of C-phosphate-G (CpG) sites has shown that the DNA methylome changes with increasing age, giving rise to genome-wide hypomethylation with site‑specific incidences of hypermethylation. This notion has received a lot of attention, as it potentially explains why aged organi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085615/ https://www.ncbi.nlm.nih.gov/pubmed/24945102 http://dx.doi.org/10.3390/biology3020403 |