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Relevance of G-quadruplex structures to pharmacogenetics

G-quadruplexes are non-canonical secondary structures formed within nucleic acids that are involved in modulating cellular processes such as replication, gene regulation, recombination and epigenetics. Within genes, there is mounting evidence of G-quadruplex involvement in transcriptional and post t...

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Detalles Bibliográficos
Autores principales: Cree, Simone L., Kennedy, Martin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085647/
https://www.ncbi.nlm.nih.gov/pubmed/25071578
http://dx.doi.org/10.3389/fphar.2014.00160

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