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Rac1 and Aurora A regulate MCAK to polarize microtubule growth in migrating endothelial cells

Endothelial cells (ECs) migrate directionally during angiogenesis and wound healing by polarizing to extracellular cues to guide directional movement. EC polarization is controlled by microtubule (MT) growth dynamics, which are regulated by MT-associated proteins (MAPs) that alter MT stability. Mito...

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Detalles Bibliográficos
Autores principales: Braun, Alexander, Dang, Kyvan, Buslig, Felinah, Baird, Michelle A., Davidson, Michael W., Waterman, Clare M., Myers, Kenneth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085700/
https://www.ncbi.nlm.nih.gov/pubmed/25002679
http://dx.doi.org/10.1083/jcb.201401063