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Manipulation of a VEGF-Notch signaling circuit drives formation of functional vascular endothelial progenitors from human pluripotent stem cells

Human pluripotent stem cell (hPSC)-derived endothelial lineage cells constitutes a promising source for therapeutic revascularization, but progress in this arena has been hampered by a lack of clinically-scalable differentiation protocols and inefficient formation of a functional vessel network inte...

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Detalles Bibliográficos
Autores principales: Sahara, Makoto, Hansson, Emil M, Wernet, Oliver, Lui, Kathy O, Später, Daniela, Chien, Kenneth R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085760/
https://www.ncbi.nlm.nih.gov/pubmed/24810299
http://dx.doi.org/10.1038/cr.2014.59

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