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Manipulation of a VEGF-Notch signaling circuit drives formation of functional vascular endothelial progenitors from human pluripotent stem cells
Human pluripotent stem cell (hPSC)-derived endothelial lineage cells constitutes a promising source for therapeutic revascularization, but progress in this arena has been hampered by a lack of clinically-scalable differentiation protocols and inefficient formation of a functional vessel network inte...
Autores principales: | Sahara, Makoto, Hansson, Emil M, Wernet, Oliver, Lui, Kathy O, Später, Daniela, Chien, Kenneth R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085760/ https://www.ncbi.nlm.nih.gov/pubmed/24810299 http://dx.doi.org/10.1038/cr.2014.59 |
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