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FIRST REPORT OF METALLO-β-LACTAMASES PRODUCING Enterobacter spp. STRAINS FROM VENEZUELA

Clinical strains of Enterobacter were isolated from Cumana's Central Hospital in Venezuela, and classified as E. cloacae (21), E. aerogenes (7), E. intermedium (1), E. sakazakii (1) and three unclassified. The strains showed high levels of resistance, especially to SXT (58.1%), CRO (48.8%), CAZ...

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Detalles Bibliográficos
Autores principales: Martínez, Dianny, Rodulfo, Hectorina E., Rodríguez, Lucy, Caña, Luisa E., Medina, Belkis, Guzman, Militza, Carreño, Numirin, Marcano, Daniel, Donato, Marcos De
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto de Medicina Tropical 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085824/
https://www.ncbi.nlm.nih.gov/pubmed/24553611
http://dx.doi.org/10.1590/S0036-46652014000100010
Descripción
Sumario:Clinical strains of Enterobacter were isolated from Cumana's Central Hospital in Venezuela, and classified as E. cloacae (21), E. aerogenes (7), E. intermedium (1), E. sakazakii (1) and three unclassified. The strains showed high levels of resistance, especially to SXT (58.1%), CRO (48.8%), CAZ (46.6%), PIP (46.4%), CIP (45.2%) and ATM (43.3%). This is the first report for South America of bla (VIM-2) in two E. cloacae and one Enterobacter sp., which also showed multiple mechanisms of resistance. Both E. cloacae showed bla (TEM-1), but only one showed bla (CTX-M-15) gene, while no bla (SHV) was detected.