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GABAergic Signaling as Therapeutic Target for Autism Spectrum Disorders
γ-Aminobutyric acid (GABA), the main inhibitory neurotransmitter in the adult brain, early in postnatal life exerts a depolarizing and excitatory action. This depends on accumulation of chloride inside the cell via the cation–chloride importer NKCC1, being the expression of the chloride exporter KCC...
Autores principales: | Cellot, Giada, Cherubini, Enrico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085902/ https://www.ncbi.nlm.nih.gov/pubmed/25072038 http://dx.doi.org/10.3389/fped.2014.00070 |
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