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DUET: a server for predicting effects of mutations on protein stability using an integrated computational approach
Cancer genome and other sequencing initiatives are generating extensive data on non-synonymous single nucleotide polymorphisms (nsSNPs) in human and other genomes. In order to understand the impacts of nsSNPs on the structure and function of the proteome, as well as to guide protein engineering, acc...
Autores principales: | Pires, Douglas E.V., Ascher, David B., Blundell, Tom L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086143/ https://www.ncbi.nlm.nih.gov/pubmed/24829462 http://dx.doi.org/10.1093/nar/gku411 |
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