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Lentiviral-mediated RNAi targeting caspase-3 inhibits apoptosis induced by serum deprivation in rat endplate chondrocytes in vitro
Current studies find that degenerated cartilage endplates (CEP) of vertebrae, with fewer diffusion areas, decrease nutrient supply and accelerate intervertebral disc degeneration. Many more apoptotic cells have been identified in degenerated than in normal endplates, and may be responsible for the d...
Autores principales: | Ding, L., Wu, J.P., Xu, G., Zhu, B., Zeng, Q.M., Li, D.F., Lu, W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Associação Brasileira de Divulgação Científica
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086170/ https://www.ncbi.nlm.nih.gov/pubmed/24878605 http://dx.doi.org/10.1590/1414-431X20143198 |
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