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Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine

Malaria inflicts an enormous burden on global human health. The emergence of parasite resistance to front-line drugs has prompted a renewed focus on the repositioning of clinically approved drugs as potential anti-malarial therapies. Antibiotics that inhibit protein translation are promising candida...

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Detalles Bibliográficos
Autores principales:	Wong, Wilson, Bai, Xiao-chen, Brown, Alan, Fernandez, Israel S, Hanssen, Eric, Condron, Melanie, Tan, Yan Hong, Baum, Jake, Scheres, Sjors HW
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2014
Materias:	Biophysics and Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086275/ https://www.ncbi.nlm.nih.gov/pubmed/24913268 http://dx.doi.org/10.7554/eLife.03080

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