Subchondral Bone Plate Thickening Precedes Chondrocyte Apoptosis and Cartilage Degradation in Spontaneous Animal Models of Osteoarthritis

Osteoarthritis (OA) is the most common joint disorder characterised by bone remodelling and cartilage degradation and associated with chondrocyte apoptosis. These processes were investigated at 10, 16, 24, and 30 weeks in Dunkin Hartley (DH) and Bristol Strain 2 (BS2) guinea pigs that develop OA spo...

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Detalles Bibliográficos
Autores principales: Zamli, Zaitunnatakhin, Robson Brown, Kate, Tarlton, John F., Adams, Mike A., Torlot, Georgina E., Cartwright, Charlie, Cook, William A., Vassilevskaja, Kristiina, Sharif, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086372/
https://www.ncbi.nlm.nih.gov/pubmed/25045687
http://dx.doi.org/10.1155/2014/606870

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