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Mitochondrial Calcium Uniporter MCU Supports Cytoplasmic Ca(2+) Oscillations, Store-Operated Ca(2+) Entry and Ca(2+)-Dependent Gene Expression in Response to Receptor Stimulation
Ca(2+) flux into mitochondria is an important regulator of cytoplasmic Ca(2+) signals, energy production and cell death pathways. Ca(2+) uptake can occur through the recently discovered mitochondrial uniporter channel (MCU) but whether the MCU is involved in shaping Ca(2+) signals and downstream res...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086884/ https://www.ncbi.nlm.nih.gov/pubmed/25004162 http://dx.doi.org/10.1371/journal.pone.0101188 |