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Mitochondrial Calcium Uniporter MCU Supports Cytoplasmic Ca(2+) Oscillations, Store-Operated Ca(2+) Entry and Ca(2+)-Dependent Gene Expression in Response to Receptor Stimulation

Ca(2+) flux into mitochondria is an important regulator of cytoplasmic Ca(2+) signals, energy production and cell death pathways. Ca(2+) uptake can occur through the recently discovered mitochondrial uniporter channel (MCU) but whether the MCU is involved in shaping Ca(2+) signals and downstream res...

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Detalles Bibliográficos
Autores principales:	Samanta, Krishna, Douglas, Sophie, Parekh, Anant B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086884/ https://www.ncbi.nlm.nih.gov/pubmed/25004162 http://dx.doi.org/10.1371/journal.pone.0101188

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