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Computed Tomography of Aortic Wall Calcifications in Aortic Dissection Patients

OBJECTIVES: To investigate the frequency of aortic calcifications at the outer edge of the false lumen and the frequency of fully circular aortic calcifications in a consecutive series of patients with aortic dissection who underwent contrast-enhanced CT. METHODS: The study population compromised of...

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Autores principales: de Jong, Pim A., Hellings, Willem E., Takx, Richard A. P., Išgum, Ivana, van Herwaarden, Joost A., Mali, Willem P. Th. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087005/
https://www.ncbi.nlm.nih.gov/pubmed/25003993
http://dx.doi.org/10.1371/journal.pone.0102036
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author de Jong, Pim A.
Hellings, Willem E.
Takx, Richard A. P.
Išgum, Ivana
van Herwaarden, Joost A.
Mali, Willem P. Th. M.
author_facet de Jong, Pim A.
Hellings, Willem E.
Takx, Richard A. P.
Išgum, Ivana
van Herwaarden, Joost A.
Mali, Willem P. Th. M.
author_sort de Jong, Pim A.
collection PubMed
description OBJECTIVES: To investigate the frequency of aortic calcifications at the outer edge of the false lumen and the frequency of fully circular aortic calcifications in a consecutive series of patients with aortic dissection who underwent contrast-enhanced CT. METHODS: The study population compromised of 69 consecutive subjects aged 60 years and older with a contrast-enhanced CT scan demonstrating an aortic dissection. All CT scans were evaluated for the frequency of aortic calcifications at the outer edge of the false lumen and the frequency of fully circular aortic calcifications by two experienced observers. Between observer reliability was evaluated by using Cohen’s Kappa. Differences between groups were tested using unpaired T test and Chi-square test. RESULTS: Presumed media calcifications were observed in 22 (32%) patients of 60 years and older and were found more frequently in chronic aortic dissection (N = 12/23, 52%) than in acute aortic dissection (N = 10/46, 22%). CONCLUSION: As the intima has been torn away by the aortic dissection it is highly likely that CT scans can visualize the calcifications in the tunica media of the aorta.
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spelling pubmed-40870052014-07-14 Computed Tomography of Aortic Wall Calcifications in Aortic Dissection Patients de Jong, Pim A. Hellings, Willem E. Takx, Richard A. P. Išgum, Ivana van Herwaarden, Joost A. Mali, Willem P. Th. M. PLoS One Research Article OBJECTIVES: To investigate the frequency of aortic calcifications at the outer edge of the false lumen and the frequency of fully circular aortic calcifications in a consecutive series of patients with aortic dissection who underwent contrast-enhanced CT. METHODS: The study population compromised of 69 consecutive subjects aged 60 years and older with a contrast-enhanced CT scan demonstrating an aortic dissection. All CT scans were evaluated for the frequency of aortic calcifications at the outer edge of the false lumen and the frequency of fully circular aortic calcifications by two experienced observers. Between observer reliability was evaluated by using Cohen’s Kappa. Differences between groups were tested using unpaired T test and Chi-square test. RESULTS: Presumed media calcifications were observed in 22 (32%) patients of 60 years and older and were found more frequently in chronic aortic dissection (N = 12/23, 52%) than in acute aortic dissection (N = 10/46, 22%). CONCLUSION: As the intima has been torn away by the aortic dissection it is highly likely that CT scans can visualize the calcifications in the tunica media of the aorta. Public Library of Science 2014-07-08 /pmc/articles/PMC4087005/ /pubmed/25003993 http://dx.doi.org/10.1371/journal.pone.0102036 Text en © 2014 de Jong et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
de Jong, Pim A.
Hellings, Willem E.
Takx, Richard A. P.
Išgum, Ivana
van Herwaarden, Joost A.
Mali, Willem P. Th. M.
Computed Tomography of Aortic Wall Calcifications in Aortic Dissection Patients
title Computed Tomography of Aortic Wall Calcifications in Aortic Dissection Patients
title_full Computed Tomography of Aortic Wall Calcifications in Aortic Dissection Patients
title_fullStr Computed Tomography of Aortic Wall Calcifications in Aortic Dissection Patients
title_full_unstemmed Computed Tomography of Aortic Wall Calcifications in Aortic Dissection Patients
title_short Computed Tomography of Aortic Wall Calcifications in Aortic Dissection Patients
title_sort computed tomography of aortic wall calcifications in aortic dissection patients
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087005/
https://www.ncbi.nlm.nih.gov/pubmed/25003993
http://dx.doi.org/10.1371/journal.pone.0102036
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