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Altered translation of GATA1 in Diamond-Blackfan anemia

Ribosomal protein haploinsufficiency occurs in diverse human diseases including Diamond-Blackfan anemia (DBA),(1,2) congenital asplenia,(3) and T-cell leukemia.(4) Yet how mutations in such ubiquitously expressed proteins result in cell-type and tissue specific defects remains a mystery.(5) Here, we...

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Detalles Bibliográficos
Autores principales:	Ludwig, Leif S., Gazda, Hanna T., Eng, Jennifer C., Eichhorn, Stephen W., Thiru, Prathapan, Ghazvinian, Roxanne, George, Tracy I., Gotlib, Jason R., Beggs, Alan H., Sieff, Colin A., Lodish, Harvey F., Lander, Eric S., Sankaran, Vijay G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087046/ https://www.ncbi.nlm.nih.gov/pubmed/24952648 http://dx.doi.org/10.1038/nm.3557

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