Comparison of effect of gamma ray irradiation on wild-type and N-terminal mutants of αA-crystallin

PURPOSE: To study the comparative structural and functional changes between wild-type (wt) and N-terminal congenital cataract causing αA-crystallin mutants (R12C, R21L, R49C, and R54C) upon exposure to different dosages of gamma rays. METHODS: Alpha A crystallin N-terminal mutants were created with...

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Detalles Bibliográficos
Autores principales: Ramkumar, Srinivasagan, Fujii, Noriko, Fujii, Norihiko, Thankappan, Bency, Sakaue, Hiroaki, Ingu, Kim, Natarajaseenivasan, Kalimuthusamy, Anbarasu, Kumarasamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087120/
https://www.ncbi.nlm.nih.gov/pubmed/25018622

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