The presence of anti-Tat antibodies in HIV-infected individuals is associated with containment of CD4(+) T-cell decay and viral load, and with delay of disease progression: results of a 3-year cohort study

BACKGROUND: Tat is a key HIV-1 virulence factor, which plays pivotal roles in virus gene expression, replication, transmission and disease progression. After release, extracellular Tat accumulates in tissues and exerts effects on both the virus and the immune system, promoting immune activation and...

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Detalles Bibliográficos
Autores principales: Bellino, Stefania, Tripiciano, Antonella, Picconi, Orietta, Francavilla, Vittorio, Longo, Olimpia, Sgadari, Cecilia, Paniccia, Giovanni, Arancio, Angela, Angarano, Gioacchino, Ladisa, Nicoletta, Lazzarin, Adriano, Tambussi, Giuseppe, Nozza, Silvia, Torti, Carlo, Focà, Emanuele, Palamara, Guido, Latini, Alessandra, Sighinolfi, Laura, Mazzotta, Francesco, Di Pietro, Massimo, Di Perri, Giovanni, Bonora, Stefano, Mercurio, Vito S, Mussini, Cristina, Gori, Andrea, Galli, Massimo, Monini, Paolo, Cafaro, Aurelio, Ensoli, Fabrizio, Ensoli, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087126/
https://www.ncbi.nlm.nih.gov/pubmed/24961156
http://dx.doi.org/10.1186/1742-4690-11-49

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