SuSPect: Enhanced Prediction of Single Amino Acid Variant (SAV) Phenotype Using Network Features

Whole-genome and exome sequencing studies reveal many genetic variants between individuals, some of which are linked to disease. Many of these variants lead to single amino acid variants (SAVs), and accurate prediction of their phenotypic impact is important. Incorporating sequence conservation and...

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Detalles Bibliográficos
Autores principales: Yates, Christopher M., Filippis, Ioannis, Kelley, Lawrence A., Sternberg, Michael J.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087249/
https://www.ncbi.nlm.nih.gov/pubmed/24810707
http://dx.doi.org/10.1016/j.jmb.2014.04.026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087249/
https://www.ncbi.nlm.nih.gov/pubmed/24810707
http://dx.doi.org/10.1016/j.jmb.2014.04.026

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