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State-Dependent Network Connectivity Determines Gating in a K(+) Channel
X-ray crystallography has provided tremendous insight into the different structural states of membrane proteins and, in particular, of ion channels. However, the molecular forces that determine the thermodynamic stability of a particular state are poorly understood. Here we analyze the different X-r...
Autores principales: | Bollepalli, Murali K., Fowler, Philip W., Rapedius, Markus, Shang, Lijun, Sansom, Mark S.P., Tucker, Stephen J., Baukrowitz, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087272/ https://www.ncbi.nlm.nih.gov/pubmed/24980796 http://dx.doi.org/10.1016/j.str.2014.04.018 |
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