Mixed Germ Cell Testicular Cancer with Left Ventricular Metastasis Presenting with Embolic Stroke and Small Bowel Tumor Seeding

Testicular germ cell tumors (GCTs) metastasize in a very predictable fashion involving the retroperitoneal nodes first followed by hematogenous spread to distant organs like lungs, liver, and brain. Metastasis to heart is an extremely rare entity for GCT and fewer than 20 cases have been reported in...

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Autores principales: Sundararajan, Srinath, Braunhut, Beth, Ahmann, Frederick, Agarwal, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087286/
https://www.ncbi.nlm.nih.gov/pubmed/25045560
http://dx.doi.org/10.1155/2014/250531
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author Sundararajan, Srinath
Braunhut, Beth
Ahmann, Frederick
Agarwal, Amit
author_facet Sundararajan, Srinath
Braunhut, Beth
Ahmann, Frederick
Agarwal, Amit
author_sort Sundararajan, Srinath
collection PubMed
description Testicular germ cell tumors (GCTs) metastasize in a very predictable fashion involving the retroperitoneal nodes first followed by hematogenous spread to distant organs like lungs, liver, and brain. Metastasis to heart is an extremely rare entity for GCT and fewer than 20 cases have been reported in the literature so far. We have summarized here a unique case of nonseminomatous germ cell tumor (NSGCT) with intracardiac metastasis resulting in systemic macroembolization to liver, spleen, brain, bowel and musculoskeletal tissues. This led to multiple adverse sequelae including ischemic stroke and bowel perforation.
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spelling pubmed-40872862014-07-20 Mixed Germ Cell Testicular Cancer with Left Ventricular Metastasis Presenting with Embolic Stroke and Small Bowel Tumor Seeding Sundararajan, Srinath Braunhut, Beth Ahmann, Frederick Agarwal, Amit Case Rep Oncol Med Case Report Testicular germ cell tumors (GCTs) metastasize in a very predictable fashion involving the retroperitoneal nodes first followed by hematogenous spread to distant organs like lungs, liver, and brain. Metastasis to heart is an extremely rare entity for GCT and fewer than 20 cases have been reported in the literature so far. We have summarized here a unique case of nonseminomatous germ cell tumor (NSGCT) with intracardiac metastasis resulting in systemic macroembolization to liver, spleen, brain, bowel and musculoskeletal tissues. This led to multiple adverse sequelae including ischemic stroke and bowel perforation. Hindawi Publishing Corporation 2014 2014-06-18 /pmc/articles/PMC4087286/ /pubmed/25045560 http://dx.doi.org/10.1155/2014/250531 Text en Copyright © 2014 Srinath Sundararajan et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Sundararajan, Srinath
Braunhut, Beth
Ahmann, Frederick
Agarwal, Amit
Mixed Germ Cell Testicular Cancer with Left Ventricular Metastasis Presenting with Embolic Stroke and Small Bowel Tumor Seeding
title Mixed Germ Cell Testicular Cancer with Left Ventricular Metastasis Presenting with Embolic Stroke and Small Bowel Tumor Seeding
title_full Mixed Germ Cell Testicular Cancer with Left Ventricular Metastasis Presenting with Embolic Stroke and Small Bowel Tumor Seeding
title_fullStr Mixed Germ Cell Testicular Cancer with Left Ventricular Metastasis Presenting with Embolic Stroke and Small Bowel Tumor Seeding
title_full_unstemmed Mixed Germ Cell Testicular Cancer with Left Ventricular Metastasis Presenting with Embolic Stroke and Small Bowel Tumor Seeding
title_short Mixed Germ Cell Testicular Cancer with Left Ventricular Metastasis Presenting with Embolic Stroke and Small Bowel Tumor Seeding
title_sort mixed germ cell testicular cancer with left ventricular metastasis presenting with embolic stroke and small bowel tumor seeding
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087286/
https://www.ncbi.nlm.nih.gov/pubmed/25045560
http://dx.doi.org/10.1155/2014/250531
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