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Interaction of LRRK2 with kinase and GTPase signaling cascades

LRRK2 is a protein that interacts with a plethora of signaling molecules, but the complexity of LRRK2 function presents a challenge for understanding the role of LRRK2 in the pathophysiology of Parkinson’s disease (PD). Studies of LRRK2 using over-expression in transgenic mice have been disappointin...

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Detalles Bibliográficos
Autores principales:	Boon, Joon Y., Dusonchet, Julien, Trengrove, Chelsea, Wolozin, Benjamin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087324/ https://www.ncbi.nlm.nih.gov/pubmed/25071441 http://dx.doi.org/10.3389/fnmol.2014.00064

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