Modelling human protein interaction networks as metric spaces has potential in disease research and drug target discovery

BACKGROUND: We have recently shown by formally modelling human protein interaction networks (PINs) as metric spaces and classified proteins into zones based on their distance from the topological centre that hub proteins are primarily centrally located. We also showed that zones closest to the netwo...

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Detalles Bibliográficos
Autores principales: Fadhal, Emad, Mwambene, Eric C, Gamieldien, Junaid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4088370/
https://www.ncbi.nlm.nih.gov/pubmed/24929653
http://dx.doi.org/10.1186/1752-0509-8-68

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