Cargando…

NKTR-061 (inhaled amikacin) delivers high lung doses in mechanically ventilated patients with pneumonia and in healthy subjects

Detalles Bibliográficos
Autores principales:	Eldon, M, Corkery, K, Gribben, D, Fink, J, Niederman, M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Poster Presentation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4088413/ http://dx.doi.org/10.1186/cc6263

Ejemplares similares

Pharmacokinetics and lung delivery of PDDS-aerosolized amikacin (NKTR-061) in intubated and mechanically ventilated patients with nosocomial pneumonia
por: Luyt, Charles-Edouard, et al.
Publicado: (2009)

High epithelial lining fluid concentrations of NKTR-061 (inhaled amikacin) twice daily achieved in pneumonic portions of lung
por: Chastre, J, et al.
Publicado: (2008)

Decrease in intravenous antibiotic use with adjunctive aerosolized amikacin treatment in intubated mechanically ventilated patients with Gram-negative pneumonia
por: Niederman, M, et al.
Publicado: (2007)

Performance of amikacin inhale: impact of supplemental oxygen and device orientation
por: Kadrichu, N, et al.
Publicado: (2015)

Inhaled ceftazidime and amikacin versus inhaled colistin in the treatment of gram negative ventilator associated pneumonia
por: Nassar, YS, et al.
Publicado: (2015)

In vitro efficiency of Amikacin Inhale, a novel drug-device delivery system
por: Kadrichu, N, et al.
Publicado: (2013)

Adjunctive inhaled amikacin in infants with ventilator-associated pneumonia optimizes the complex antimicrobial therapy: pilot study
por: Levchenko, Bohdan, et al.
Publicado: (2023)

Laryngitis after inhalation of liposomal amikacin
por: Morita, Atsuho, et al.
Publicado: (2022)

Inhaled amikacin versus placebo to prevent ventilator-associated pneumonia: the AMIKINHAL double-blind multicentre randomised controlled trial protocol
por: Tavernier, Elsa, et al.
Publicado: (2021)

Human Abuse Potential of the New Opioid Analgesic Molecule NKTR-181 Compared with Oxycodone
por: Webster, Lynn, et al.
Publicado: (2018)

Liposomal Amikacin Inhalation Suspension-induced Pneumonitis
por: Kidogawa, Moe, et al.
Publicado: (2022)

Inhaled amikacin for pneumonia treatment and dissemination prevention: an experimental model of severe monolateral Pseudomonas aeruginosa pneumonia
por: Motos, Ana, et al.
Publicado: (2023)

A comparative study between effect of combined intravenous and nebulized amikacin versus intravenous amikacin alone in mechanically ventilated patients with ventilator-associated pneumonia (VAP)
por: El Fawy, Dalia M., et al.
Publicado: (2020)

NKTR-102 Efficacy versus irinotecan in a mouse model of brain metastases of breast cancer
por: Adkins, Chris E., et al.
Publicado: (2015)

Ventilator-associated pneumonia
por: Ranzani, Otavio T., et al.
Publicado: (2022)

Selective expansion of regulatory T cells by NKTR-358 in healthy volunteers and patients with systemic lupus erythematosus
por: Fanton, Christie, et al.
Publicado: (2022)

Amikacin Liposome Inhalation Suspension (ALIS) Penetrates Non-tuberculous Mycobacterial Biofilms and Enhances Amikacin Uptake Into Macrophages
por: Zhang, Jimin, et al.
Publicado: (2018)

Nonclinical pharmacokinetics and activity of etirinotecan pegol (NKTR-102), a long-acting topoisomerase 1 inhibitor, in multiple cancer models
por: Hoch, Ute, et al.
Publicado: (2014)

Cost effectiveness in treating ventilator-associated pneumonia
por: Niederman, Michael S
Publicado: (2001)

Evaluating the efficacy of inhaled amikacin as an adjunct to intravenous combination therapy (ceftazidime and amikacin) in pediatric cystic fibrosis pulmonary exacerbation
por: Rakhshan, Amin, et al.
Publicado: (2023)

Sputum concentration of amikacin varies with nebulizer efficiency measured in vitro in patients on mechanical ventilators
por: Dequin, P, et al.
Publicado: (2004)

Effect of extended infusion of meropenem and nebulized amikacin on Gram-negative multidrug-resistant ventilator-associated pneumonia
por: Ammar, Mona Ahmed, et al.
Publicado: (2018)

Initial In Vivo Evaluation of a Novel Amikacin-Deoxycholate Hydrophobic Salt Delivers New Insights on Amikacin Partition in Blood and Tissues
por: Xiroudaki, Styliani, et al.
Publicado: (2021)

Amikacin-loaded niosome nanoparticles improve amikacin activity against antibiotic-resistant Klebsiella pneumoniae strains
por: Rahmati, Mohamad, et al.
Publicado: (2022)

O061. Frontal thermography in healthy individuals and headache patients: reliability of the method
por: Voiticovschi-Iosob, Cristina, et al.
Publicado: (2015)

Ventilator-associated pneumonia: present understanding and ongoing debates
por: Nair, Girish B., et al.
Publicado: (2014)

What COVID-19 Has Taught Us: Ventilator-associated Pneumonia Is Back!
por: Niederman, Michael S.
Publicado: (2022)

Safety, Tolerability, and Pharmacokinetics of RT234 (Vardenafil Inhalation Powder): A First-in-Human, Ascending Single- and Multiple-Dose Study in Healthy Subjects
por: Eldon, Michael A., et al.
Publicado: (2021)

Positive Effect of Liposomal Amikacin for Inhalation on Mycobacterium abcessus in Cystic Fibrosis Patients
por: Caimmi, Davide, et al.
Publicado: (2018)

Heteroresistance to Amikacin in Carbapenem-Resistant Klebsiella pneumoniae Strains
por: Zhang, Feiyang, et al.
Publicado: (2021)

P061 CPAP Investigation Results: Physician vs Scientist delivered. Is there a difference in CPAP compliance and uptake?
por: Doyle, G, et al.
Publicado: (2023)

Modeling the receptor pharmacology, pharmacokinetics, and pharmacodynamics of NKTR-214, a kinetically-controlled interleukin-2 (IL2) receptor agonist for cancer immunotherapy
por: Charych, Deborah, et al.
Publicado: (2017)

Delivered dose with jet and mesh nebulisers during spontaneous breathing, noninvasive ventilation and mechanical ventilation using adult lung models
por: Ari, Arzu, et al.
Publicado: (2021)

Amikacin Liposome Inhalation Suspension: A Review in Mycobacterium avium Complex Lung Disease
por: Shirley, Matt
Publicado: (2019)

Pharmacokinetics of Salmeterol and Fluticasone Propionate Delivered in Combination via Easyhaler and Diskus Dry Powder Inhalers in Healthy Subjects
por: Kirjavainen, Merja, et al.
Publicado: (2018)

In Vitro antibiotic combinations of Colistin, Meropenem, Amikacin, and Amoxicillin/clavulanate against multidrug-resistant Klebsiella pneumonia isolated from patients with ventilator-associated pneumonia
por: Bayatinejad, Ghazal, et al.
Publicado: (2023)

A Population Dose–Response Model for Inhaled Technosphere Insulin Administered to Healthy Subjects
por: Rüppel, D, et al.
Publicado: (2017)

Pulmonary Deposition and Elimination of Liposomal Amikacin for Inhalation and Effect on Macrophage Function after Administration in Rats
por: Malinin, Vladimir, et al.
Publicado: (2016)

Correction to: Amikacin Liposome Inhalation Suspension: A Review in Mycobacterium avium Complex Lung Disease
por: Shirley, Matt
Publicado: (2019)

Dimension milestone - Release 0.6.1 of dimensions
por: Hoffmann, H, et al.
Publicado: (1996)

Cannot write session to /tmp/vufind_sessions/sess_f4qg7ol26t3nan197h18m3v2as