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Aptamer-targeted Antigen Delivery
Effective therapeutic vaccines often require activation of T cell-mediated immunity. Robust T cell activation, including CD8 T cell responses, can be achieved using antibodies or antibody fragments to direct antigens of interest to professional antigen presenting cells. This approach represents an i...
Autores principales: | Wengerter, Brian C, Katakowski, Joseph A, Rosenberg, Jacob M, Park, Chae Gyu, Almo, Steven C, Palliser, Deborah, Levy, Matthew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4089008/ https://www.ncbi.nlm.nih.gov/pubmed/24682172 http://dx.doi.org/10.1038/mt.2014.51 |
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