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Vitamin D receptor activation: cardiovascular and renal implications

The effects of vitamin D receptor activation on cardiovascular diseases, especially hypertension and cardiac dysfunction, are areas of active investigation. This article reviews the current state of knowledge about vitamin D receptor activation with respect to blood pressure, heart, and vascular hea...

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Detalles Bibliográficos
Autores principales: Nigwekar, Sagar U, Thadhani, Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4089580/
https://www.ncbi.nlm.nih.gov/pubmed/25019025
http://dx.doi.org/10.1038/kisup.2013.89
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author Nigwekar, Sagar U
Thadhani, Ravi
author_facet Nigwekar, Sagar U
Thadhani, Ravi
author_sort Nigwekar, Sagar U
collection PubMed
description The effects of vitamin D receptor activation on cardiovascular diseases, especially hypertension and cardiac dysfunction, are areas of active investigation. This article reviews the current state of knowledge about vitamin D receptor activation with respect to blood pressure, heart, and vascular health, as well as to chronic kidney disease and end-stage renal disease. Potential biological mechanisms, the role of vitamin D-binding protein, and data from observational and randomized controlled trials on this topic are summarized.
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spelling pubmed-40895802014-07-11 Vitamin D receptor activation: cardiovascular and renal implications Nigwekar, Sagar U Thadhani, Ravi Kidney Int Suppl (2011) Review The effects of vitamin D receptor activation on cardiovascular diseases, especially hypertension and cardiac dysfunction, are areas of active investigation. This article reviews the current state of knowledge about vitamin D receptor activation with respect to blood pressure, heart, and vascular health, as well as to chronic kidney disease and end-stage renal disease. Potential biological mechanisms, the role of vitamin D-binding protein, and data from observational and randomized controlled trials on this topic are summarized. Nature Publishing Group 2013-12 2013-11-27 /pmc/articles/PMC4089580/ /pubmed/25019025 http://dx.doi.org/10.1038/kisup.2013.89 Text en Copyright © 2013 International Society of Nephrology
spellingShingle Review
Nigwekar, Sagar U
Thadhani, Ravi
Vitamin D receptor activation: cardiovascular and renal implications
title Vitamin D receptor activation: cardiovascular and renal implications
title_full Vitamin D receptor activation: cardiovascular and renal implications
title_fullStr Vitamin D receptor activation: cardiovascular and renal implications
title_full_unstemmed Vitamin D receptor activation: cardiovascular and renal implications
title_short Vitamin D receptor activation: cardiovascular and renal implications
title_sort vitamin d receptor activation: cardiovascular and renal implications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4089580/
https://www.ncbi.nlm.nih.gov/pubmed/25019025
http://dx.doi.org/10.1038/kisup.2013.89
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