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Vitamin D receptor activation: cardiovascular and renal implications
The effects of vitamin D receptor activation on cardiovascular diseases, especially hypertension and cardiac dysfunction, are areas of active investigation. This article reviews the current state of knowledge about vitamin D receptor activation with respect to blood pressure, heart, and vascular hea...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4089580/ https://www.ncbi.nlm.nih.gov/pubmed/25019025 http://dx.doi.org/10.1038/kisup.2013.89 |
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author | Nigwekar, Sagar U Thadhani, Ravi |
author_facet | Nigwekar, Sagar U Thadhani, Ravi |
author_sort | Nigwekar, Sagar U |
collection | PubMed |
description | The effects of vitamin D receptor activation on cardiovascular diseases, especially hypertension and cardiac dysfunction, are areas of active investigation. This article reviews the current state of knowledge about vitamin D receptor activation with respect to blood pressure, heart, and vascular health, as well as to chronic kidney disease and end-stage renal disease. Potential biological mechanisms, the role of vitamin D-binding protein, and data from observational and randomized controlled trials on this topic are summarized. |
format | Online Article Text |
id | pubmed-4089580 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-40895802014-07-11 Vitamin D receptor activation: cardiovascular and renal implications Nigwekar, Sagar U Thadhani, Ravi Kidney Int Suppl (2011) Review The effects of vitamin D receptor activation on cardiovascular diseases, especially hypertension and cardiac dysfunction, are areas of active investigation. This article reviews the current state of knowledge about vitamin D receptor activation with respect to blood pressure, heart, and vascular health, as well as to chronic kidney disease and end-stage renal disease. Potential biological mechanisms, the role of vitamin D-binding protein, and data from observational and randomized controlled trials on this topic are summarized. Nature Publishing Group 2013-12 2013-11-27 /pmc/articles/PMC4089580/ /pubmed/25019025 http://dx.doi.org/10.1038/kisup.2013.89 Text en Copyright © 2013 International Society of Nephrology |
spellingShingle | Review Nigwekar, Sagar U Thadhani, Ravi Vitamin D receptor activation: cardiovascular and renal implications |
title | Vitamin D receptor activation: cardiovascular and renal implications |
title_full | Vitamin D receptor activation: cardiovascular and renal implications |
title_fullStr | Vitamin D receptor activation: cardiovascular and renal implications |
title_full_unstemmed | Vitamin D receptor activation: cardiovascular and renal implications |
title_short | Vitamin D receptor activation: cardiovascular and renal implications |
title_sort | vitamin d receptor activation: cardiovascular and renal implications |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4089580/ https://www.ncbi.nlm.nih.gov/pubmed/25019025 http://dx.doi.org/10.1038/kisup.2013.89 |
work_keys_str_mv | AT nigwekarsagaru vitamindreceptoractivationcardiovascularandrenalimplications AT thadhaniravi vitamindreceptoractivationcardiovascularandrenalimplications |