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T-cell co-stimulatory blockade in kidney transplantation: back to the bench

It is believed that blocking positive T-cell co-stimulatory pathways should lead to long-term graft acceptance. Despite the exciting initial achievements in experimental animal models, targeting co-stimulatory pathways has shown to be much more complex in the clinic. In addition to multiple binding...

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Detalles Bibliográficos
Autores principales: Riella, Leonardo V, Sayegh, Mohamed H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4089598/
https://www.ncbi.nlm.nih.gov/pubmed/25018899
http://dx.doi.org/10.1038/kisup.2011.8