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Rational approaches to the treatment of hypertension: drug therapy—monotherapy, combination, or fixed-dose combination?

Blood pressure (BP) control is inadequate worldwide. Many clinical trials suggest that BP is not satisfactorily controlled using monotherapy in most patients. Free drug or fixed-dose combinations are other therapeutic options. The advantages and disadvantages for different treatment approaches are d...

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Detalles Bibliográficos
Autor principal: Canbakan, Başol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4089686/
https://www.ncbi.nlm.nih.gov/pubmed/25028639
http://dx.doi.org/10.1038/kisup.2013.75
Descripción
Sumario:Blood pressure (BP) control is inadequate worldwide. Many clinical trials suggest that BP is not satisfactorily controlled using monotherapy in most patients. Free drug or fixed-dose combinations are other therapeutic options. The advantages and disadvantages for different treatment approaches are discussed in this review.