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Structure and Dynamics of the HIV-1 Frameshift Element RNA

[Image: see text] The HIV-1 ribosomal frameshift element is highly structured, regulates translation of all virally encoded enzymes, and is a promising therapeutic target. The prior model for this motif contains two helices separated by a three-nucleotide bulge. Modifications to this model were sugg...

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Detalles Bibliográficos
Autores principales: Low, Justin T., Garcia-Miranda, Pablo, Mouzakis, Kathryn D., Gorelick, Robert J., Butcher, Samuel E., Weeks, Kevin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4089884/
https://www.ncbi.nlm.nih.gov/pubmed/24926888
http://dx.doi.org/10.1021/bi5004926