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Structure and Dynamics of the HIV-1 Frameshift Element RNA
[Image: see text] The HIV-1 ribosomal frameshift element is highly structured, regulates translation of all virally encoded enzymes, and is a promising therapeutic target. The prior model for this motif contains two helices separated by a three-nucleotide bulge. Modifications to this model were sugg...
Autores principales: | Low, Justin T., Garcia-Miranda, Pablo, Mouzakis, Kathryn D., Gorelick, Robert J., Butcher, Samuel E., Weeks, Kevin M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4089884/ https://www.ncbi.nlm.nih.gov/pubmed/24926888 http://dx.doi.org/10.1021/bi5004926 |
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