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Prevalence and Causes of Blindness and Visual Impairment and Their Associated Risk Factors, in Three Tribal Areas of Andhra Pradesh, India

OBJECTIVE: To assess the prevalence of blindness and visual impairment (VI), their associated causes and underlying risk factors in three tribal areas of Andhra Pradesh, India and compare this data in conjunction with data from other countries with low and middle income settings. METHODS: Using a va...

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Autores principales: Singh, Nakul, Eeda, Shiva Shankar, Gudapati, Bala Krishna, Reddy, Srinivasa, Kanade, Pushkar, Shantha, Ghanshyam Palamaner Subash, Rani, Padmaja Kumari, Chakrabarti, Subhabrata, Khanna, Rohit C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090120/
https://www.ncbi.nlm.nih.gov/pubmed/25007075
http://dx.doi.org/10.1371/journal.pone.0100644
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author Singh, Nakul
Eeda, Shiva Shankar
Gudapati, Bala Krishna
Reddy, Srinivasa
Kanade, Pushkar
Shantha, Ghanshyam Palamaner Subash
Rani, Padmaja Kumari
Chakrabarti, Subhabrata
Khanna, Rohit C
author_facet Singh, Nakul
Eeda, Shiva Shankar
Gudapati, Bala Krishna
Reddy, Srinivasa
Kanade, Pushkar
Shantha, Ghanshyam Palamaner Subash
Rani, Padmaja Kumari
Chakrabarti, Subhabrata
Khanna, Rohit C
author_sort Singh, Nakul
collection PubMed
description OBJECTIVE: To assess the prevalence of blindness and visual impairment (VI), their associated causes and underlying risk factors in three tribal areas of Andhra Pradesh, India and compare this data in conjunction with data from other countries with low and middle income settings. METHODS: Using a validated Rapid Assessment of Avoidable Blindness methodology, a two stage sampling survey was performed in these areas involving probability proportionate to size sampling and compact segment sampling methods. Blindness, VI and severe visual impairment (SVI) were defined as per the WHO guidelines and Indian definitions. RESULTS: Based on a prior enumeration, 7281 (97.1%) subjects were enrolled (mean age  = 61.0+/−7.9 years). Based on the presenting visual acuity (PVA), the prevalences of VI, SVI and blindness were 16.9% (95% CI: 15.7–18.1), 2.9% (95% CI: 2.5–3.4), and 2.3% (95% CI: 1.9–2.7), respectively. When based on the Pinhole corrected visual acuity (PCVA), the prevalences were lower in VI (6.2%, 95% CI: 5.4–6.9), SVI (1.5%, 95% CI: 1.2–1.9) and blindness (2.1%, 95% CI: 1.7–2.5). Refractive error was the major cause of VI (71.4%), whereas, cataract was the major cause of SVI and blindness (70.3%). Based on the PVA, the odds ratio (OR) of blindness increased in the age groups of 60–69 years (OR = 3.8, 95% CI: 2.8, 5.1), 70–79 years (OR = 10.6, 95% CI: 7.2, 15.5) and 80 years and above (OR = 30.7, 95% CI: 19.2, 49). The ORs were relatively higher in females (OR = 1.3, 95% CI: 1.0, 1.6) and illiterate subjects (OR = 4.3, 95% CI: 2.2, 8.5), but lower in those wearing glasses (OR = 0.2, 95% CI: 0.1, 0.4). CONCLUSIONS: This is perhaps the first study to assess the prevalence of blindness and VI in these tribal regions and the majority of the causes of blindness and SVI were avoidable (88.5%). These findings may be useful for planning eye care services in these underserved regions.
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spelling pubmed-40901202014-07-14 Prevalence and Causes of Blindness and Visual Impairment and Their Associated Risk Factors, in Three Tribal Areas of Andhra Pradesh, India Singh, Nakul Eeda, Shiva Shankar Gudapati, Bala Krishna Reddy, Srinivasa Kanade, Pushkar Shantha, Ghanshyam Palamaner Subash Rani, Padmaja Kumari Chakrabarti, Subhabrata Khanna, Rohit C PLoS One Research Article OBJECTIVE: To assess the prevalence of blindness and visual impairment (VI), their associated causes and underlying risk factors in three tribal areas of Andhra Pradesh, India and compare this data in conjunction with data from other countries with low and middle income settings. METHODS: Using a validated Rapid Assessment of Avoidable Blindness methodology, a two stage sampling survey was performed in these areas involving probability proportionate to size sampling and compact segment sampling methods. Blindness, VI and severe visual impairment (SVI) were defined as per the WHO guidelines and Indian definitions. RESULTS: Based on a prior enumeration, 7281 (97.1%) subjects were enrolled (mean age  = 61.0+/−7.9 years). Based on the presenting visual acuity (PVA), the prevalences of VI, SVI and blindness were 16.9% (95% CI: 15.7–18.1), 2.9% (95% CI: 2.5–3.4), and 2.3% (95% CI: 1.9–2.7), respectively. When based on the Pinhole corrected visual acuity (PCVA), the prevalences were lower in VI (6.2%, 95% CI: 5.4–6.9), SVI (1.5%, 95% CI: 1.2–1.9) and blindness (2.1%, 95% CI: 1.7–2.5). Refractive error was the major cause of VI (71.4%), whereas, cataract was the major cause of SVI and blindness (70.3%). Based on the PVA, the odds ratio (OR) of blindness increased in the age groups of 60–69 years (OR = 3.8, 95% CI: 2.8, 5.1), 70–79 years (OR = 10.6, 95% CI: 7.2, 15.5) and 80 years and above (OR = 30.7, 95% CI: 19.2, 49). The ORs were relatively higher in females (OR = 1.3, 95% CI: 1.0, 1.6) and illiterate subjects (OR = 4.3, 95% CI: 2.2, 8.5), but lower in those wearing glasses (OR = 0.2, 95% CI: 0.1, 0.4). CONCLUSIONS: This is perhaps the first study to assess the prevalence of blindness and VI in these tribal regions and the majority of the causes of blindness and SVI were avoidable (88.5%). These findings may be useful for planning eye care services in these underserved regions. Public Library of Science 2014-07-09 /pmc/articles/PMC4090120/ /pubmed/25007075 http://dx.doi.org/10.1371/journal.pone.0100644 Text en © 2014 Singh et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Singh, Nakul
Eeda, Shiva Shankar
Gudapati, Bala Krishna
Reddy, Srinivasa
Kanade, Pushkar
Shantha, Ghanshyam Palamaner Subash
Rani, Padmaja Kumari
Chakrabarti, Subhabrata
Khanna, Rohit C
Prevalence and Causes of Blindness and Visual Impairment and Their Associated Risk Factors, in Three Tribal Areas of Andhra Pradesh, India
title Prevalence and Causes of Blindness and Visual Impairment and Their Associated Risk Factors, in Three Tribal Areas of Andhra Pradesh, India
title_full Prevalence and Causes of Blindness and Visual Impairment and Their Associated Risk Factors, in Three Tribal Areas of Andhra Pradesh, India
title_fullStr Prevalence and Causes of Blindness and Visual Impairment and Their Associated Risk Factors, in Three Tribal Areas of Andhra Pradesh, India
title_full_unstemmed Prevalence and Causes of Blindness and Visual Impairment and Their Associated Risk Factors, in Three Tribal Areas of Andhra Pradesh, India
title_short Prevalence and Causes of Blindness and Visual Impairment and Their Associated Risk Factors, in Three Tribal Areas of Andhra Pradesh, India
title_sort prevalence and causes of blindness and visual impairment and their associated risk factors, in three tribal areas of andhra pradesh, india
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090120/
https://www.ncbi.nlm.nih.gov/pubmed/25007075
http://dx.doi.org/10.1371/journal.pone.0100644
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