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CP-673451, a platelet-derived growth-factor receptor inhibitor, suppresses lung cancer cell proliferation and migration

Lung cancer is the leading cause of cancer mortality in the world. Although some advances in lung cancer therapy have been made, patient survival is still poor. The platelet-derived growth factor receptors (PDGFRs) and their ligands play critical roles in the regulation of many cancer cell processes...

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Detalles Bibliográficos
Autores principales: Xi, Yuling, Chen, Ming, Liu, Xinmin, Lu, Zhongmin, Ding, Yi, Li, Datong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090130/
https://www.ncbi.nlm.nih.gov/pubmed/25050066
http://dx.doi.org/10.2147/OTT.S62946

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