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Epithelial inflammation resulting from an inherited loss-of-function mutation in EGFR
Epidermal growth factor receptor (EGFR) signaling is fundamentally important for tissue homeostasis through EGFR/ligand interactions that stimulate numerous signal transduction pathways. Aberrant EGFR signaling has been reported in inflammatory and malignant diseases but thus far no primary inherite...
Autores principales: | Campbell, Patrick, Morton, Penny, Takeichi, Takuya, Salam, Amr, Roberts, Nerys, Proudfoot, Laura E., Mellerio, Jemima E., Aminu, Kingi, Wellington, Cheryl, Patil, Sachin N., Akiyama, Masashi, Liu, Lu, McMillan, James R., Aristodemou, Sophia, Ishida-Yamamoto, Akemi, Abdul-Wahab, Alya, Petrof, Gabriela, Fong, Kenneth, Harnchoowong, Sarawin, Stone, Kristina, Harper, John I., McLean, W. H. Irwin, Simpson, Michael A., Parsons, Maddy, McGrath, John A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090136/ https://www.ncbi.nlm.nih.gov/pubmed/24691054 http://dx.doi.org/10.1038/jid.2014.164 |
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