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α-Actinin-2 Mediates Spine Morphology and Assembly of the Post-Synaptic Density in Hippocampal Neurons
Dendritic spines are micron-sized protrusions that constitute the primary post-synaptic sites of excitatory neurotransmission in the brain. Spines mature from a filopodia-like protrusion into a mushroom-shaped morphology with a post-synaptic density (PSD) at its tip. Modulation of the actin cytoskel...
Autores principales: | Hodges, Jennifer L., Vilchez, Samuel Martin, Asmussen, Hannelore, Whitmore, Leanna A., Horwitz, Alan Rick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090192/ https://www.ncbi.nlm.nih.gov/pubmed/25007055 http://dx.doi.org/10.1371/journal.pone.0101770 |
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