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α-Actinin-2 Mediates Spine Morphology and Assembly of the Post-Synaptic Density in Hippocampal Neurons

Dendritic spines are micron-sized protrusions that constitute the primary post-synaptic sites of excitatory neurotransmission in the brain. Spines mature from a filopodia-like protrusion into a mushroom-shaped morphology with a post-synaptic density (PSD) at its tip. Modulation of the actin cytoskel...

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Detalles Bibliográficos
Autores principales: Hodges, Jennifer L., Vilchez, Samuel Martin, Asmussen, Hannelore, Whitmore, Leanna A., Horwitz, Alan Rick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090192/
https://www.ncbi.nlm.nih.gov/pubmed/25007055
http://dx.doi.org/10.1371/journal.pone.0101770

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