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Redox-Triggered C–C Coupling of Alcohols and Vinyl Epoxides: Diastereo- and Enantioselective Formation of All-Carbon Quaternary Centers via tert-(Hydroxy)-Prenylation

[Image: see text] Iridium catalyzed primary alcohol oxidation triggers reductive C–O bond cleavage of isoprene oxide to form aldehyde-allyliridium pairs that combine to form products of tert-(hydroxy)-prenylation, a motif found in >2000 terpenoid natural products. Curtin–Hammett effects are explo...

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Detalles Bibliográficos
Autores principales:	Feng, Jiajie, Garza, Victoria J., Krische, Michael J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090370/ https://www.ncbi.nlm.nih.gov/pubmed/24915473 http://dx.doi.org/10.1021/ja504625m

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