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Radiofrequency Ablation Compared to Surgery for the Treatment of Benign Thyroid Nodules
Objective. Benign thyroid nodules are a common occurrence whose only remedy, in case of symptoms, has always been surgery until the advent of new techniques, such as radiofrequency ablation (RFA). This study aimed at evaluating RFA efficacy, tolerability, and costs and comparing them to hemithyroide...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090443/ https://www.ncbi.nlm.nih.gov/pubmed/25045352 http://dx.doi.org/10.1155/2014/934595 |
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author | Bernardi, Stella Dobrinja, Chiara Fabris, Bruno Bazzocchi, Gabriele Sabato, Nicoletta Ulcigrai, Veronica Giacca, Massimo Barro, Enrica De Manzini, Nicolò Stacul, Fulvio |
author_facet | Bernardi, Stella Dobrinja, Chiara Fabris, Bruno Bazzocchi, Gabriele Sabato, Nicoletta Ulcigrai, Veronica Giacca, Massimo Barro, Enrica De Manzini, Nicolò Stacul, Fulvio |
author_sort | Bernardi, Stella |
collection | PubMed |
description | Objective. Benign thyroid nodules are a common occurrence whose only remedy, in case of symptoms, has always been surgery until the advent of new techniques, such as radiofrequency ablation (RFA). This study aimed at evaluating RFA efficacy, tolerability, and costs and comparing them to hemithyroidectomy for the treatment of benign thyroid nodules. Design and Methods. 37 patients who underwent RFA were retrospectively compared to 74 patients surgically treated, either in a standard inpatient or in a short-stay surgical regimen. Efficacy, tolerability, and costs were compared. The contribution of final pathology was also taken into account. Results. RFA reduced nodular volume by 70% after 12 months and it was an effective method for treating nodule-related clinical problems, but it was not as effective as surgery for the treatment of hot nodules. RFA and surgery were both safe, although RFA had less complications and pain was rare. RFA costed €1,661.50, surgery costed €4,556.30, and short-stay surgery costed €4,139.40 per patient. RFA, however, did not allow for any pathologic analysis of the nodules, which, in 6 patients who had undergone surgery (8%), revealed that the nodules harboured malignant cells. Conclusions. RFA might transform our approach to benign thyroid nodules. |
format | Online Article Text |
id | pubmed-4090443 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-40904432014-07-20 Radiofrequency Ablation Compared to Surgery for the Treatment of Benign Thyroid Nodules Bernardi, Stella Dobrinja, Chiara Fabris, Bruno Bazzocchi, Gabriele Sabato, Nicoletta Ulcigrai, Veronica Giacca, Massimo Barro, Enrica De Manzini, Nicolò Stacul, Fulvio Int J Endocrinol Clinical Study Objective. Benign thyroid nodules are a common occurrence whose only remedy, in case of symptoms, has always been surgery until the advent of new techniques, such as radiofrequency ablation (RFA). This study aimed at evaluating RFA efficacy, tolerability, and costs and comparing them to hemithyroidectomy for the treatment of benign thyroid nodules. Design and Methods. 37 patients who underwent RFA were retrospectively compared to 74 patients surgically treated, either in a standard inpatient or in a short-stay surgical regimen. Efficacy, tolerability, and costs were compared. The contribution of final pathology was also taken into account. Results. RFA reduced nodular volume by 70% after 12 months and it was an effective method for treating nodule-related clinical problems, but it was not as effective as surgery for the treatment of hot nodules. RFA and surgery were both safe, although RFA had less complications and pain was rare. RFA costed €1,661.50, surgery costed €4,556.30, and short-stay surgery costed €4,139.40 per patient. RFA, however, did not allow for any pathologic analysis of the nodules, which, in 6 patients who had undergone surgery (8%), revealed that the nodules harboured malignant cells. Conclusions. RFA might transform our approach to benign thyroid nodules. Hindawi Publishing Corporation 2014 2014-06-22 /pmc/articles/PMC4090443/ /pubmed/25045352 http://dx.doi.org/10.1155/2014/934595 Text en Copyright © 2014 Stella Bernardi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Clinical Study Bernardi, Stella Dobrinja, Chiara Fabris, Bruno Bazzocchi, Gabriele Sabato, Nicoletta Ulcigrai, Veronica Giacca, Massimo Barro, Enrica De Manzini, Nicolò Stacul, Fulvio Radiofrequency Ablation Compared to Surgery for the Treatment of Benign Thyroid Nodules |
title | Radiofrequency Ablation Compared to Surgery for the Treatment of Benign Thyroid Nodules |
title_full | Radiofrequency Ablation Compared to Surgery for the Treatment of Benign Thyroid Nodules |
title_fullStr | Radiofrequency Ablation Compared to Surgery for the Treatment of Benign Thyroid Nodules |
title_full_unstemmed | Radiofrequency Ablation Compared to Surgery for the Treatment of Benign Thyroid Nodules |
title_short | Radiofrequency Ablation Compared to Surgery for the Treatment of Benign Thyroid Nodules |
title_sort | radiofrequency ablation compared to surgery for the treatment of benign thyroid nodules |
topic | Clinical Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090443/ https://www.ncbi.nlm.nih.gov/pubmed/25045352 http://dx.doi.org/10.1155/2014/934595 |
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