The Cardioprotective Actions of Hydrogen Sulfide in Acute Myocardial Infarction and Heart Failure

It has now become universally accepted that hydrogen sulfide (H(2)S), previously considered only as a lethal toxin, has robust cytoprotective actions in multiple organ systems. The diverse signaling profile of H(2)S impacts multiple pathways to exert cytoprotective actions in a number of pathologica...

Descripción completa

Detalles Bibliográficos
Autores principales: Polhemus, David J., Calvert, John W., Butler, Javed, Lefer, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090472/
https://www.ncbi.nlm.nih.gov/pubmed/25045576
http://dx.doi.org/10.1155/2014/768607
Descripción
Sumario:It has now become universally accepted that hydrogen sulfide (H(2)S), previously considered only as a lethal toxin, has robust cytoprotective actions in multiple organ systems. The diverse signaling profile of H(2)S impacts multiple pathways to exert cytoprotective actions in a number of pathological states. This paper will review the recently described cardioprotective actions of hydrogen sulfide in both myocardial ischemia/reperfusion injury and congestive heart failure.

Ejemplares similares