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The Cardioprotective Actions of Hydrogen Sulfide in Acute Myocardial Infarction and Heart Failure

It has now become universally accepted that hydrogen sulfide (H(2)S), previously considered only as a lethal toxin, has robust cytoprotective actions in multiple organ systems. The diverse signaling profile of H(2)S impacts multiple pathways to exert cytoprotective actions in a number of pathologica...

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Detalles Bibliográficos
Autores principales: Polhemus, David J., Calvert, John W., Butler, Javed, Lefer, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090472/
https://www.ncbi.nlm.nih.gov/pubmed/25045576
http://dx.doi.org/10.1155/2014/768607
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author Polhemus, David J.
Calvert, John W.
Butler, Javed
Lefer, David J.
author_facet Polhemus, David J.
Calvert, John W.
Butler, Javed
Lefer, David J.
author_sort Polhemus, David J.
collection PubMed
description It has now become universally accepted that hydrogen sulfide (H(2)S), previously considered only as a lethal toxin, has robust cytoprotective actions in multiple organ systems. The diverse signaling profile of H(2)S impacts multiple pathways to exert cytoprotective actions in a number of pathological states. This paper will review the recently described cardioprotective actions of hydrogen sulfide in both myocardial ischemia/reperfusion injury and congestive heart failure.
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spelling pubmed-40904722014-07-20 The Cardioprotective Actions of Hydrogen Sulfide in Acute Myocardial Infarction and Heart Failure Polhemus, David J. Calvert, John W. Butler, Javed Lefer, David J. Scientifica (Cairo) Review Article It has now become universally accepted that hydrogen sulfide (H(2)S), previously considered only as a lethal toxin, has robust cytoprotective actions in multiple organ systems. The diverse signaling profile of H(2)S impacts multiple pathways to exert cytoprotective actions in a number of pathological states. This paper will review the recently described cardioprotective actions of hydrogen sulfide in both myocardial ischemia/reperfusion injury and congestive heart failure. Hindawi Publishing Corporation 2014 2014-06-22 /pmc/articles/PMC4090472/ /pubmed/25045576 http://dx.doi.org/10.1155/2014/768607 Text en Copyright © 2014 David J. Polhemus et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Polhemus, David J.
Calvert, John W.
Butler, Javed
Lefer, David J.
The Cardioprotective Actions of Hydrogen Sulfide in Acute Myocardial Infarction and Heart Failure
title The Cardioprotective Actions of Hydrogen Sulfide in Acute Myocardial Infarction and Heart Failure
title_full The Cardioprotective Actions of Hydrogen Sulfide in Acute Myocardial Infarction and Heart Failure
title_fullStr The Cardioprotective Actions of Hydrogen Sulfide in Acute Myocardial Infarction and Heart Failure
title_full_unstemmed The Cardioprotective Actions of Hydrogen Sulfide in Acute Myocardial Infarction and Heart Failure
title_short The Cardioprotective Actions of Hydrogen Sulfide in Acute Myocardial Infarction and Heart Failure
title_sort cardioprotective actions of hydrogen sulfide in acute myocardial infarction and heart failure
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090472/
https://www.ncbi.nlm.nih.gov/pubmed/25045576
http://dx.doi.org/10.1155/2014/768607
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