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Her-2 Positive Gastric Cancer Presented with Thrombocytopenia and Skin Involvement: A Case Report
Gastric cancer is the 5th most frequent cancer around the world and the 3rd most frequent reason of deaths due to cancer. Every year, about 1 million new cases are taking place, with varying geographical distribution. Gastric cancer is often metastatic to liver, lungs, and bones in hematogenous way,...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090488/ https://www.ncbi.nlm.nih.gov/pubmed/25045559 http://dx.doi.org/10.1155/2014/194636 |
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author | Arslan, Deniz Uysal, Mukremin Tatlı, Ali Murat Gunduz, Seyda Goksu, Sema Sezgin Başsorgun, Cumhur İbrahim Coskun, Hasan Senol Bozcuk, Hakan Savaş, Burhan |
author_facet | Arslan, Deniz Uysal, Mukremin Tatlı, Ali Murat Gunduz, Seyda Goksu, Sema Sezgin Başsorgun, Cumhur İbrahim Coskun, Hasan Senol Bozcuk, Hakan Savaş, Burhan |
author_sort | Arslan, Deniz |
collection | PubMed |
description | Gastric cancer is the 5th most frequent cancer around the world and the 3rd most frequent reason of deaths due to cancer. Every year, about 1 million new cases are taking place, with varying geographical distribution. Gastric cancer is often metastatic to liver, lungs, and bones in hematogenous way, to peripheral lymph nodes in lymphogenous way, and to peripheral tissues in adjacency way, yet bone marrow (BM) and cutaneous metastasis are quite seldom. Pancytopenia is a more frequent finding identified in BM metastasis of solid organ cancers, and isolated thrombocytopenia is less often. The human epidermal growth factor 2 (HER-2) is positive in gastric cancer at a rate of 7–34%. Here, we have presented our HER-2 positive gastric cancer incident which presented with BM and cutaneous metastasis, and has no 18F-fluoro-2-deoxi-D-glucose (FDG) involvement except bone metastases. |
format | Online Article Text |
id | pubmed-4090488 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-40904882014-07-20 Her-2 Positive Gastric Cancer Presented with Thrombocytopenia and Skin Involvement: A Case Report Arslan, Deniz Uysal, Mukremin Tatlı, Ali Murat Gunduz, Seyda Goksu, Sema Sezgin Başsorgun, Cumhur İbrahim Coskun, Hasan Senol Bozcuk, Hakan Savaş, Burhan Case Rep Oncol Med Case Report Gastric cancer is the 5th most frequent cancer around the world and the 3rd most frequent reason of deaths due to cancer. Every year, about 1 million new cases are taking place, with varying geographical distribution. Gastric cancer is often metastatic to liver, lungs, and bones in hematogenous way, to peripheral lymph nodes in lymphogenous way, and to peripheral tissues in adjacency way, yet bone marrow (BM) and cutaneous metastasis are quite seldom. Pancytopenia is a more frequent finding identified in BM metastasis of solid organ cancers, and isolated thrombocytopenia is less often. The human epidermal growth factor 2 (HER-2) is positive in gastric cancer at a rate of 7–34%. Here, we have presented our HER-2 positive gastric cancer incident which presented with BM and cutaneous metastasis, and has no 18F-fluoro-2-deoxi-D-glucose (FDG) involvement except bone metastases. Hindawi Publishing Corporation 2014 2014-06-23 /pmc/articles/PMC4090488/ /pubmed/25045559 http://dx.doi.org/10.1155/2014/194636 Text en Copyright © 2014 Deniz Arslan et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Arslan, Deniz Uysal, Mukremin Tatlı, Ali Murat Gunduz, Seyda Goksu, Sema Sezgin Başsorgun, Cumhur İbrahim Coskun, Hasan Senol Bozcuk, Hakan Savaş, Burhan Her-2 Positive Gastric Cancer Presented with Thrombocytopenia and Skin Involvement: A Case Report |
title | Her-2 Positive Gastric Cancer Presented with Thrombocytopenia and Skin Involvement: A Case Report |
title_full | Her-2 Positive Gastric Cancer Presented with Thrombocytopenia and Skin Involvement: A Case Report |
title_fullStr | Her-2 Positive Gastric Cancer Presented with Thrombocytopenia and Skin Involvement: A Case Report |
title_full_unstemmed | Her-2 Positive Gastric Cancer Presented with Thrombocytopenia and Skin Involvement: A Case Report |
title_short | Her-2 Positive Gastric Cancer Presented with Thrombocytopenia and Skin Involvement: A Case Report |
title_sort | her-2 positive gastric cancer presented with thrombocytopenia and skin involvement: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090488/ https://www.ncbi.nlm.nih.gov/pubmed/25045559 http://dx.doi.org/10.1155/2014/194636 |
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