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Andrographolide induces vascular smooth muscle cell apoptosis through a SHP-1-PP2A-p38MAPK-p53 cascade
The abnormal growth of vascular smooth muscle cells (VSMCs) is considered a critical pathogenic process in inflammatory vascular diseases. We have previously demonstrated that protein phosphatase 2 A (PP2A)-mediated NF-κB dephosphorylation contributes to the anti-inflammatory properties of andrograp...
Autores principales: | Chen, Yu-Ying, Hsieh, Cheng-Ying, Jayakumar, Thanasekaran, Lin, Kuan-Hung, Chou, Duen-Suey, Lu, Wan-Jung, Hsu, Ming-Jen, Sheu, Joen-Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090621/ https://www.ncbi.nlm.nih.gov/pubmed/25007834 http://dx.doi.org/10.1038/srep05651 |
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