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Inhibitory effect of ent-Sauchinone on amyloidogenesis via inhibition of STAT3-mediated NF-κB activation in cultured astrocytes and microglial BV-2 cells
BACKGROUND: ent-Sauchinone is a polyphenolic compound found in plants belonging to the lignan family. ent-Sauchinone has been shown to modulate the expression of inflammatory factors through the nuclear factor-kappa B (NF-κB) signaling pathway. It is well known that neuroinflammation is associated w...
Autores principales: | Song, Suk-Young, Jung, Yu Yeon, Hwang, Chul Ju, Lee, Hee Peom, Sok, Chang Hyun, Kim, Joo Hwan, Lee, Sang Min, Seo, Hyun Ok, Hyun, Byung Kook, Choi, Dong Young, Han, Sang Bae, Ham, Young Wan, Hwang, Bang Yeon, Hong, Jin Tae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090659/ https://www.ncbi.nlm.nih.gov/pubmed/24985096 http://dx.doi.org/10.1186/1742-2094-11-118 |
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