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BI-69A11 enhances susceptibility of colon cancer cells to mda-7/IL-24-induced growth inhibition by targeting Akt

BACKGROUND: Akt and its downstream signalling pathways contribute to the aetiology and progression of colorectal carcinoma (CRC). Targeting the Akt pathway is an attractive strategy but few chemotherapeutic drugs have been used to treat CRC with only limited success. BI-69A11, a small molecule inhib...

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Detalles Bibliográficos
Autores principales:	Pal, I, Sarkar, S, Rajput, S, Dey, K K, Chakraborty, S, Dash, R, Das, S K, Sarkar, D, Barile, E, De, S K, Pellecchia, M, Fisher, P B, Mandal, M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090725/ https://www.ncbi.nlm.nih.gov/pubmed/24892445 http://dx.doi.org/10.1038/bjc.2014.227

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