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Assessing the function of homologous recombination DNA repair in malignant pleural effusion (MPE) samples

BACKGROUND: Patients with malignant pleural effusions (MPEs) generally have advanced disease with poor survival and few therapeutic options. Cells within MPEs may be used to stratify patients for targeted therapy. Targeted therapy with poly(ADP ribose) polymerase inhibitors (PARPi) depends on identi...

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Detalles Bibliográficos
Autores principales:	Patterson, M J, Sutton, R E, Forrest, I, Sharrock, R, Lane, M, Kaufmann, A, O'Donnell, R, Edmondson, R J, Wilson, B T, Curtin, N J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090730/ https://www.ncbi.nlm.nih.gov/pubmed/24867690 http://dx.doi.org/10.1038/bjc.2014.261

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