Epidemiology of basal cell carcinoma in the United Kingdom: incidence, lifestyle factors, and comorbidities

BACKGROUND: Little is known about the epidemiology of basal cell carcinoma (BCC). METHODS: Using the Clinical Practice Research Datalink, we calculated annual incidence rates. In a case–control analysis, we examined lifestyle factors and comorbidities. RESULTS: Incidence rose significantly between 2...

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Detalles Bibliográficos
Autores principales: Reinau, D, Surber, C, Jick, S S, Meier, C R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Epidemiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090732/
https://www.ncbi.nlm.nih.gov/pubmed/24874476
http://dx.doi.org/10.1038/bjc.2014.265
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author Reinau, D
Surber, C
Jick, S S
Meier, C R
author_facet Reinau, D
Surber, C
Jick, S S
Meier, C R
author_sort Reinau, D
collection PubMed
description BACKGROUND: Little is known about the epidemiology of basal cell carcinoma (BCC). METHODS: Using the Clinical Practice Research Datalink, we calculated annual incidence rates. In a case–control analysis, we examined lifestyle factors and comorbidities. RESULTS: Incidence rose significantly between 2000 and 2011. Basal cell carcinoma risk was increased in alcohol drinkers (slightly) and immunocompromised patients, but reduced in smokers and individuals with abnormal weight. CONCLUSIONS: Basal cell carcinoma places a growing public health burden. Lifestyle factors do not play a major role in pathogenesis, but immunosuppression is important.
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spelling pubmed-40907322015-07-01 Epidemiology of basal cell carcinoma in the United Kingdom: incidence, lifestyle factors, and comorbidities Reinau, D Surber, C Jick, S S Meier, C R Br J Cancer Epidemiology BACKGROUND: Little is known about the epidemiology of basal cell carcinoma (BCC). METHODS: Using the Clinical Practice Research Datalink, we calculated annual incidence rates. In a case–control analysis, we examined lifestyle factors and comorbidities. RESULTS: Incidence rose significantly between 2000 and 2011. Basal cell carcinoma risk was increased in alcohol drinkers (slightly) and immunocompromised patients, but reduced in smokers and individuals with abnormal weight. CONCLUSIONS: Basal cell carcinoma places a growing public health burden. Lifestyle factors do not play a major role in pathogenesis, but immunosuppression is important. Nature Publishing Group 2014-07-01 2014-05-29 /pmc/articles/PMC4090732/ /pubmed/24874476 http://dx.doi.org/10.1038/bjc.2014.265 Text en Copyright © 2014 Cancer Research UK http://creativecommons.org/licenses/by-nc-sa/3.0/ From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/
spellingShingle Epidemiology
Reinau, D
Surber, C
Jick, S S
Meier, C R
Epidemiology of basal cell carcinoma in the United Kingdom: incidence, lifestyle factors, and comorbidities
title Epidemiology of basal cell carcinoma in the United Kingdom: incidence, lifestyle factors, and comorbidities
title_full Epidemiology of basal cell carcinoma in the United Kingdom: incidence, lifestyle factors, and comorbidities
title_fullStr Epidemiology of basal cell carcinoma in the United Kingdom: incidence, lifestyle factors, and comorbidities
title_full_unstemmed Epidemiology of basal cell carcinoma in the United Kingdom: incidence, lifestyle factors, and comorbidities
title_short Epidemiology of basal cell carcinoma in the United Kingdom: incidence, lifestyle factors, and comorbidities
title_sort epidemiology of basal cell carcinoma in the united kingdom: incidence, lifestyle factors, and comorbidities
topic Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090732/
https://www.ncbi.nlm.nih.gov/pubmed/24874476
http://dx.doi.org/10.1038/bjc.2014.265
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