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Profiling and targeting of cellular bioenergetics: inhibition of pancreatic cancer cell proliferation
BACKGROUND: Targeting both mitochondrial bioenergetics and glycolysis pathway is an effective way to inhibit proliferation of tumour cells, including those that are resistant to conventional chemotherapeutics. METHODS: In this study, using the Seahorse 96-well Extracellular Flux Analyzer, we mapped...
Autores principales: | Cheng, G, Zielonka, J, McAllister, D, Tsai, S, Dwinell, M B, Kalyanaraman, B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090735/ https://www.ncbi.nlm.nih.gov/pubmed/24867695 http://dx.doi.org/10.1038/bjc.2014.272 |
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