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The heat shock protein-CD91 pathway mediates tumor immunosurveillance

Tumor immunosurveillance can be readily observed in mice and humans. Here, we examine how T-cell responses are primed during tumorigenesis, a condition in which immunostimulatory antigens are extraordinarily scarce. We recently demonstrated that the HSP-CD91 pathway is indispensable for antigen cros...

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Detalles Bibliográficos
Autores principales: Zhou, Yu Jerry, Binder, Robert Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091098/
https://www.ncbi.nlm.nih.gov/pubmed/25050192
http://dx.doi.org/10.4161/onci.28222
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author Zhou, Yu Jerry
Binder, Robert Julian
author_facet Zhou, Yu Jerry
Binder, Robert Julian
author_sort Zhou, Yu Jerry
collection PubMed
description Tumor immunosurveillance can be readily observed in mice and humans. Here, we examine how T-cell responses are primed during tumorigenesis, a condition in which immunostimulatory antigens are extraordinarily scarce. We recently demonstrated that the HSP-CD91 pathway is indispensable for antigen cross-presentation, and thus immunosurveillance, in cancer.
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spelling pubmed-40910982015-04-25 The heat shock protein-CD91 pathway mediates tumor immunosurveillance Zhou, Yu Jerry Binder, Robert Julian Oncoimmunology Author's View Tumor immunosurveillance can be readily observed in mice and humans. Here, we examine how T-cell responses are primed during tumorigenesis, a condition in which immunostimulatory antigens are extraordinarily scarce. We recently demonstrated that the HSP-CD91 pathway is indispensable for antigen cross-presentation, and thus immunosurveillance, in cancer. Landes Bioscience 2014-04-25 /pmc/articles/PMC4091098/ /pubmed/25050192 http://dx.doi.org/10.4161/onci.28222 Text en Copyright © 2014 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Zhou, Yu Jerry
Binder, Robert Julian
The heat shock protein-CD91 pathway mediates tumor immunosurveillance
title The heat shock protein-CD91 pathway mediates tumor immunosurveillance
title_full The heat shock protein-CD91 pathway mediates tumor immunosurveillance
title_fullStr The heat shock protein-CD91 pathway mediates tumor immunosurveillance
title_full_unstemmed The heat shock protein-CD91 pathway mediates tumor immunosurveillance
title_short The heat shock protein-CD91 pathway mediates tumor immunosurveillance
title_sort heat shock protein-cd91 pathway mediates tumor immunosurveillance
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091098/
https://www.ncbi.nlm.nih.gov/pubmed/25050192
http://dx.doi.org/10.4161/onci.28222
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