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The heat shock protein-CD91 pathway mediates tumor immunosurveillance
Tumor immunosurveillance can be readily observed in mice and humans. Here, we examine how T-cell responses are primed during tumorigenesis, a condition in which immunostimulatory antigens are extraordinarily scarce. We recently demonstrated that the HSP-CD91 pathway is indispensable for antigen cros...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091098/ https://www.ncbi.nlm.nih.gov/pubmed/25050192 http://dx.doi.org/10.4161/onci.28222 |
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author | Zhou, Yu Jerry Binder, Robert Julian |
author_facet | Zhou, Yu Jerry Binder, Robert Julian |
author_sort | Zhou, Yu Jerry |
collection | PubMed |
description | Tumor immunosurveillance can be readily observed in mice and humans. Here, we examine how T-cell responses are primed during tumorigenesis, a condition in which immunostimulatory antigens are extraordinarily scarce. We recently demonstrated that the HSP-CD91 pathway is indispensable for antigen cross-presentation, and thus immunosurveillance, in cancer. |
format | Online Article Text |
id | pubmed-4091098 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Landes Bioscience |
record_format | MEDLINE/PubMed |
spelling | pubmed-40910982015-04-25 The heat shock protein-CD91 pathway mediates tumor immunosurveillance Zhou, Yu Jerry Binder, Robert Julian Oncoimmunology Author's View Tumor immunosurveillance can be readily observed in mice and humans. Here, we examine how T-cell responses are primed during tumorigenesis, a condition in which immunostimulatory antigens are extraordinarily scarce. We recently demonstrated that the HSP-CD91 pathway is indispensable for antigen cross-presentation, and thus immunosurveillance, in cancer. Landes Bioscience 2014-04-25 /pmc/articles/PMC4091098/ /pubmed/25050192 http://dx.doi.org/10.4161/onci.28222 Text en Copyright © 2014 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
spellingShingle | Author's View Zhou, Yu Jerry Binder, Robert Julian The heat shock protein-CD91 pathway mediates tumor immunosurveillance |
title | The heat shock protein-CD91 pathway mediates tumor immunosurveillance |
title_full | The heat shock protein-CD91 pathway mediates tumor immunosurveillance |
title_fullStr | The heat shock protein-CD91 pathway mediates tumor immunosurveillance |
title_full_unstemmed | The heat shock protein-CD91 pathway mediates tumor immunosurveillance |
title_short | The heat shock protein-CD91 pathway mediates tumor immunosurveillance |
title_sort | heat shock protein-cd91 pathway mediates tumor immunosurveillance |
topic | Author's View |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091098/ https://www.ncbi.nlm.nih.gov/pubmed/25050192 http://dx.doi.org/10.4161/onci.28222 |
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