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BECN1 is involved in the initiation of mitophagy: It facilitates PARK2 translocation to mitochondria
The autophagy protein BECN1/Beclin 1 is known to play a central role in autophagosome formation and maturation. The results presented here demonstrate that BECN1 interacts with the Parkinson disease-related protein PARK2. This interaction does not require PARK2 translocation to mitochondria and occu...
Autores principales: | Choubey, Vinay, Cagalinec, Michal, Liiv, Joanna, Safiulina, Dzhamilja, Hickey, Miriam A, Kuum, Malle, Liiv, Mailis, Anwar, Tahira, Eskelinen, Eeva-Liisa, Kaasik, Allen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091171/ https://www.ncbi.nlm.nih.gov/pubmed/24879156 http://dx.doi.org/10.4161/auto.28615 |
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