Cargando…

Rh(I)-Catalyzed Intermolecular Hydroacylation: Enantioselective Cross-Coupling of Aldehydes and Ketoamides

[Image: see text] Under Rh(I) catalysis, α-ketoamides undergo intermolecular hydroacylation with aliphatic aldehydes. A newly designed Josiphos ligand enables access to α-acyloxyamides with high atom-economy and enantioselectivity. On the basis of mechanistic and kinetic studies, we propose a pathwa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kou, Kevin G. M., Le, Diane N., Dong, Vy M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091274/ https://www.ncbi.nlm.nih.gov/pubmed/24937681 http://dx.doi.org/10.1021/ja504296x

Ejemplares similares

Rh-catalyzed desymmetrization of α-quaternary centers by isomerization-hydroacylation
por: Park, Jung-Woo, et al.
Publicado: (2015)

Traceless Rhodium‐Catalyzed Hydroacylation Using Alkyl Aldehydes: The Enantioselective Synthesis of β‐Aryl Ketones
por: Bouisseau, Anaïs, et al.
Publicado: (2016)

Mechanistic insights into hydroacylation with non-chelating aldehydes
por: Murphy, Stephen K., et al.
Publicado: (2015)

Azine-N-oxides as effective controlling groups for Rh-catalysed intermolecular alkyne hydroacylation
por: Moseley, Daniel F., et al.
Publicado: (2021)

Enantioselective Synthesis of Polycyclic Nitrogen Heterocycles by Rh-Catalyzed Alkene Hydroacylation: Constructing Six-Membered Rings in the Absence of Chelation Assistance
por: Du, Xiang-Wei, et al.
Publicado: (2014)

α‐Amidoaldehydes as Substrates in Rhodium‐Catalyzed Intermolecular Alkyne Hydroacylation: The Synthesis of α‐Amidoketones
por: Pal, Ritashree, et al.
Publicado: (2020)

Catalytic Enantioselective Pictet–Spengler Reaction of α‐Ketoamides Catalyzed by a Single H‐Bond Donor Organocatalyst
por: Andres, Rémi, et al.
Publicado: (2022)

Regioselective Hydroacylation of 1,3-Dienes by Cobalt Catalysis
por: Chen, Qing-An, et al.
Publicado: (2014)

Enantioselective Rh(I)-Catalyzed C–H Arylation of Ferroceneformaldehydes
por: Liu, Chen-Xu, et al.
Publicado: (2023)

Iridium‐Catalyzed Enantioselective Intermolecular Indole C2‐Allylation
por: Rossi‐Ashton, James A., et al.
Publicado: (2020)

Rh(I)–Bisphosphine-Catalyzed Asymmetric, Intermolecular Hydroheteroarylation of α-Substituted Acrylate Derivatives
por: Filloux, Claire M., et al.
Publicado: (2014)

Highly Enantioselective, Intermolecular Hydroamination of Allenyl Esters Catalyzed by Bifunctional Phosphinothioureas
por: Fang, Yuan-Qing, et al.
Publicado: (2014)

Enantioselective PCCP Brønsted acid-catalyzed aminalization of aldehydes
por: Kamlar, Martin, et al.
Publicado: (2021)

Reagent-controlled regiodivergent intermolecular cyclization of 2-aminobenzothiazoles with β-ketoesters and β-ketoamides
por: Roslan, Irwan Iskandar, et al.
Publicado: (2017)

Enantioselective Redox-Neutral Coupling of Aldehydes and Alkenes by an Iron-Catalyzed “Catch–Release” Tethering Approach
por: Li, Jing, et al.
Publicado: (2018)

Synthesis of α,β-unsaturated ketones through nickel-catalysed aldehyde-free hydroacylation of alkynes
por: Rhlee, Joon Ho, et al.
Publicado: (2022)

Potent inhibition of enterovirus D68 and human rhinoviruses by dipeptidyl aldehydes and α-ketoamides
por: Kim, Yunjeong, et al.
Publicado: (2016)

Highly Enantioselective Hiyama Cross-Coupling via Rh-Catalyzed Allylic Arylation of Racemic Allyl Chlorides
por: González, Jesús, et al.
Publicado: (2019)

Development of (Trimethylsilyl)ethyl Ester Protected Enolates and Applications in Palladium-Catalyzed Enantioselective Allylic Alkylation: Intermolecular Cross-Coupling of Functionalized Electrophiles
por: Reeves, Corey M., et al.
Publicado: (2014)

Enantioselective Imidation of Sulfides via Enzyme-Catalyzed Intermolecular Nitrogen-Atom Transfer
por: Farwell, Christopher C., et al.
Publicado: (2014)

Pd/Xiang-Phos-catalyzed enantioselective intermolecular carboheterofunctionalization under mild conditions
por: Tao, Mengna, et al.
Publicado: (2020)

Nickel/Brønsted Acid-Catalyzed Chemo- and Enantioselective Intermolecular Hydroamination of Conjugated Dienes
por: Long, Jiao, et al.
Publicado: (2019)

Rhodium-catalyzed intermolecular enantioselective Alder–ene type reaction of cyclopentenes with silylacetylenes
por: Zhang, Dongquan, et al.
Publicado: (2021)

Reactivity and Chemoselectivity of Allenes in Rh(I)-Catalyzed Intermolecular (5 + 2) Cycloadditions with Vinylcyclopropanes: Allene-Mediated Rhodacycle Formation Can Poison Rh(I)-Catalyzed Cycloadditions
por: Hong, Xin, et al.
Publicado: (2014)

Rh-Catalyzed Highly Enantioselective Synthesis of Aliphatic Sulfonyl Fluorides
por: Moku, Balakrishna, et al.
Publicado: (2019)

2-Aminobenzaldehydes as Versatile Substrates for Rhodium-Catalyzed Alkyne Hydroacylation: Application to Dihydroquinolone Synthesis**
por: Castaing, Matthias, et al.
Publicado: (2013)

Nickel-Catalyzed Enantioselective Coupling of Aldehydes and Electron-Deficient 1,3-Dienes Following an Inverse Regiochemical Course
por: Davies, Thomas Q., et al.
Publicado: (2022)

NHC-Catalyzed Asymmetric Synthesis of Functionalized Succinimides from Enals and α-Ketoamides
por: Wang, Lei, et al.
Publicado: (2015)

Copper-catalyzed synthesis of α-ketoamides using water and dioxygen as the oxygen source
por: Xiao, Yuanyuan, et al.
Publicado: (2020)

Enantioselective Aldol Addition of Acetaldehyde to Aromatic Aldehydes Catalyzed by Proline-Based Carboligases
por: Saifuddin, Mohammad, et al.
Publicado: (2020)

Ligand-enabled Ir-catalyzed intermolecular diastereoselective and enantioselective allylic alkylation of 3-substituted indoles
por: Zhang, Xiao, et al.
Publicado: (2015)

Iridium-catalyzed hydroacylation reactions of C1-substituted oxabenzonorbornadienes with salicylaldehyde: an experimental and computational study
por: Ho, Angel, et al.
Publicado: (2022)

Enantioselective reductive multicomponent coupling reactions between isatins and aldehydes
por: Horwitz, Matthew A., et al.
Publicado: (2015)

Rh-Catalyzed Intermolecular Syn-Carboamination of Alkenes via a Transient Directing Group
por: Piou, Tiffany, et al.
Publicado: (2015)

Nickel-catalyzed Suzuki–Miyaura cross-couplings of aldehydes
por: Guo, Lin, et al.
Publicado: (2019)

Stereoselective Gold(I)-Catalyzed Intermolecular Hydroalkoxlation of Alkynes
por: Veenboer, Richard M. P., et al.
Publicado: (2015)

Continuous-flow enantioselective α-aminoxylation of aldehydes catalyzed by a polystyrene-immobilized hydroxyproline
por: Cambeiro, Xacobe C, et al.
Publicado: (2011)

Highly Enantioselective Addition of Phenylethynylzinc to Aldehydes Catalyzed by Chiral Cyclopropane-Based Amino Alcohols
por: Zheng, Bing, et al.
Publicado: (2013)

Photoredox cobalt-catalyzed regio-, diastereo- and enantioselective propargylation of aldehydes via propargyl radicals
por: Wang, Lei, et al.
Publicado: (2023)

Gold(I)-Catalyzed Intermolecular Aryloxyvinylation with Acetylene Gas
por: Medina-Gil, Tania, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_om1q74aami7ah9n0hfp3jaj8sk