Hydroxyl-Directed Stereoselective Diboration of Alkenes

[Image: see text] An alkoxide-catalyzed directed diboration of alkenyl alcohols is described. This reaction occurs in a stereoselective fashion and is demonstrated with cyclic and acyclic homoallylic and bishomoallylic alcohol substrates. After oxidation, the reaction generates 1,2-diols such that t...

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Autores principales: Blaisdell, Thomas P., Caya, Thomas C., Zhang, Liang, Sanz-Marco, Amparo, Morken, James P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091278/
https://www.ncbi.nlm.nih.gov/pubmed/24941137
http://dx.doi.org/10.1021/ja504228p
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author Blaisdell, Thomas P.
Caya, Thomas C.
Zhang, Liang
Sanz-Marco, Amparo
Morken, James P.
author_facet Blaisdell, Thomas P.
Caya, Thomas C.
Zhang, Liang
Sanz-Marco, Amparo
Morken, James P.
author_sort Blaisdell, Thomas P.
collection PubMed
description [Image: see text] An alkoxide-catalyzed directed diboration of alkenyl alcohols is described. This reaction occurs in a stereoselective fashion and is demonstrated with cyclic and acyclic homoallylic and bishomoallylic alcohol substrates. After oxidation, the reaction generates 1,2-diols such that the process represents a method for the stereoselective directed dihydroxylation of alkenes.
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spelling pubmed-40912782015-06-18 Hydroxyl-Directed Stereoselective Diboration of Alkenes Blaisdell, Thomas P. Caya, Thomas C. Zhang, Liang Sanz-Marco, Amparo Morken, James P. J Am Chem Soc [Image: see text] An alkoxide-catalyzed directed diboration of alkenyl alcohols is described. This reaction occurs in a stereoselective fashion and is demonstrated with cyclic and acyclic homoallylic and bishomoallylic alcohol substrates. After oxidation, the reaction generates 1,2-diols such that the process represents a method for the stereoselective directed dihydroxylation of alkenes. American Chemical Society 2014-06-18 2014-07-02 /pmc/articles/PMC4091278/ /pubmed/24941137 http://dx.doi.org/10.1021/ja504228p Text en Copyright © 2014 American Chemical Society Terms of Use (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html)
spellingShingle Blaisdell, Thomas P.
Caya, Thomas C.
Zhang, Liang
Sanz-Marco, Amparo
Morken, James P.
Hydroxyl-Directed Stereoselective Diboration of Alkenes
title Hydroxyl-Directed Stereoselective Diboration of Alkenes
title_full Hydroxyl-Directed Stereoselective Diboration of Alkenes
title_fullStr Hydroxyl-Directed Stereoselective Diboration of Alkenes
title_full_unstemmed Hydroxyl-Directed Stereoselective Diboration of Alkenes
title_short Hydroxyl-Directed Stereoselective Diboration of Alkenes
title_sort hydroxyl-directed stereoselective diboration of alkenes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091278/
https://www.ncbi.nlm.nih.gov/pubmed/24941137
http://dx.doi.org/10.1021/ja504228p
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AT sanzmarcoamparo hydroxyldirectedstereoselectivediborationofalkenes
AT morkenjamesp hydroxyldirectedstereoselectivediborationofalkenes

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